Respiratory Effects of Fine and Ultrafine Particles from Indoor Sources—A Randomized Sham-Controlled Exposure Study of Healthy Volunteers

Vanessa J. Soppa, Roel P. F. Schins, Frauke Hennig, Bryan Hellack, Ulrich Quass, Heinz Kaminski, Thomas A. J. Kuhlbusch, Barbara Hoffmann and Gudrun Weinmayr
Additional contact information
Vanessa J. Soppa: IUF-Leibniz Research Institute for Environmental Medicine, Auf'm Hennekamp 50, 40225 Düsseldorf, Germany
Roel P. F. Schins: IUF-Leibniz Research Institute for Environmental Medicine, Auf'm Hennekamp 50, 40225 Düsseldorf, Germany
Frauke Hennig: IUF-Leibniz Research Institute for Environmental Medicine, Auf'm Hennekamp 50, 40225 Düsseldorf, Germany
Bryan Hellack: Air Quality and Sustainable Nanotechnology Unit, Institut für Energie- und Umwelttechnik (IUTA) e.V., Bliersheimer Straße 58–60, 47229 Duisburg, Germany
Ulrich Quass: Air Quality and Sustainable Nanotechnology Unit, Institut für Energie- und Umwelttechnik (IUTA) e.V., Bliersheimer Straße 58–60, 47229 Duisburg, Germany
Heinz Kaminski: Air Quality and Sustainable Nanotechnology Unit, Institut für Energie- und Umwelttechnik (IUTA) e.V., Bliersheimer Straße 58–60, 47229 Duisburg, Germany
Thomas A. J. Kuhlbusch: Air Quality and Sustainable Nanotechnology Unit, Institut für Energie- und Umwelttechnik (IUTA) e.V., Bliersheimer Straße 58–60, 47229 Duisburg, Germany
Barbara Hoffmann: IUF-Leibniz Research Institute for Environmental Medicine, Auf'm Hennekamp 50, 40225 Düsseldorf, Germany
Gudrun Weinmayr: IUF-Leibniz Research Institute for Environmental Medicine, Auf'm Hennekamp 50, 40225 Düsseldorf, Germany

IJERPH, 2014, vol. 11, issue 7, 1-19

Abstract: Particulate air pollution is linked to impaired respiratory health. We analyzed particle emissions from common indoor sources (candles burning (CB), toasting bread (TB), frying sausages (FS)) and lung function in 55 healthy volunteers (mean age 33.0 years) in a randomized cross-over controlled exposure study. Lung-deposited particle surface area concentration (PSC), size-specific particle number concentration (PNC) up to 10 µm, and particle mass concentration (PMC) of PM 1 , PM 2.5 and PM 10 were determined during exposure (2 h). FEV 1 , FVC and MEF 25 %–75% was measured before, 4 h and 24 h after exposure. Wilcoxon-rank sum tests (comparing exposure scenarios) and mixed linear regression using particle concentrations and adjusting for personal characteristics, travel time and transportation means before exposure sessions were performed. While no effect was seen comparing the exposure scenarios and in the unadjusted model, inverse associations were found for PMC from CB and FS in relation to FEV 1 and MEF 25 %–75% . with a change in 10 µg/m 3 in PM 2.5 from CB being associated with a change in FEV 1 of ?19 mL (95%-confidence interval:?43; 5) after 4 h. PMC from TB and PNC of UFP were not associated with lung function changes, but PSC from CB was. Elevated indoor fine particles from certain sources may be associated with small decreases in lung function in healthy adults.

Keywords: fine and ultrafine particles; controlled exposure; indoor sources; lung function (search for similar items in EconPapers)
JEL-codes: I I1 I3 Q Q5 (search for similar items in EconPapers)
Date: 2014
References: View complete reference list from CitEc
Citations: View citations in EconPapers (6)

Downloads: (external link)
https://www.mdpi.com/1660-4601/11/7/6871/pdf (application/pdf)
https://www.mdpi.com/1660-4601/11/7/6871/ (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:gam:jijerp:v:11:y:2014:i:7:p:6871-6889:d:37814

Access Statistics for this article

IJERPH is currently edited by Ms. Jenna Liu

More articles in IJERPH from MDPI
Bibliographic data for series maintained by MDPI Indexing Manager ().