Factors Associated with Mortality in Patients with COVID-19 from a Hospital in Northern Peru

Mario J. Valladares-Garrido, Aldo Alvarez-Risco, Luis E. Vasquez-Elera, Christopher G. Valdiviezo-Morales, Raisa N. Martinez-Rivera, Annel L. Cruz-Zapata, César Johan Pereira-Victorio, Elian Garcia-Peña, Virgilio E. Failoc-Rojas (), Shyla Del-Aguila-Arcentales, Neal M. Davies and Jaime A. Yáñez ()
Additional contact information
Mario J. Valladares-Garrido: South American Center for Education and Research in Public Health, Universidad Norbert Wiener, Lima 15046, Peru
Aldo Alvarez-Risco: Carrera de Negocios Internacionales, Facultad de Ciencias Empresariales y Económicas, Universidad de Lima, Lima 15023, Peru
Luis E. Vasquez-Elera: Servicio de Gastroenterología, Hospital Cayetano Heredia, Piura 20002, Peru
Christopher G. Valdiviezo-Morales: Escuela de Medicina, Universidad Nacional de Piura, Piura 20002, Peru
Raisa N. Martinez-Rivera: Escuela de Medicina, Universidad Nacional de Piura, Piura 20002, Peru
Annel L. Cruz-Zapata: Escuela de Medicina, Universidad Nacional de Piura, Piura 20002, Peru
César Johan Pereira-Victorio: Escuela de Medicina, Universidad Continental, Lima 15046, Peru
Elian Garcia-Peña: Escuela de Medicina, Universidad Nacional de Piura, Piura 20002, Peru
Virgilio E. Failoc-Rojas: Unidad de Investigación para la Generación y Síntesis de Evidencias en Salud, Universidad San Ignacio de Loyola, Lima 15024, Peru
Shyla Del-Aguila-Arcentales: Escuela de Posgrado, Universidad San Ignacio de Loyola, Lima 15024, Peru
Neal M. Davies: Faculty of Pharmacy & Pharmaceutical Sciences, University of Alberta, Edmonton, AB T6G 2H1, Canada
Jaime A. Yáñez: Escuela Profesional de Medicina Humana, Universidad Privada San Juan Bautista, Filial de Ica, Ica 11004, Peru

Sustainability, 2023, vol. 15, issue 5, 1-14

Abstract: We aimed to identify the factors associated with mortality in patients with COVID-19 from the hospitalization service of the Cayetano Heredia Hospital, Piura, Peru, from May to June 2020. A prospective study was conducted in hospitalized patients with a confirmed diagnosis of COVID-19 through serological and/or molecular reactive testing. The dependent variable was death due to COVID-19, and the independent variables were the epidemiological, clinical and laboratory characteristics of the patient. The chi-square test and the non-parametric Mann–Whitney U test were used, with a significance level of 5%. Of 301 patients with COVID-19, the majority of them were male (66.1%), and the mean age was 58.63 years. Of the patients analyzed, 41.3% of them died, 40.2% of them were obese and 59.8% of them had hepatic steatosis. The three most frequent signs/symptoms were dyspnea (90.03%), fatigue (90.03%) and a cough (84.72%). Being an older adult ( p = 0.011), being hospitalized in the ICU ( p = 0.001), overweight ( p = 0.016), obese ( p = 0.021) and having compromised consciousness ( p = 0.039) and thrombocytopenia ( p = 0.024) were associated with mortality due to COVID-19. Overall, the mortality rate due to COVID-19 was 41.3%. Having an older age, being hospitalized in the ICU, overweight, obese and having compromised consciousness and thrombocytopenia were positively associated with mortality in patients with COVID-19. These findings highlight the need to establish an adequate system of surveillance and epidemiological education in hospitals and communities in the event of new outbreaks, especially in rural and northern Peru.

Keywords: COVID-19; coronavirus infections; mortality; prospective studies; Peru; death (search for similar items in EconPapers)
JEL-codes: O13 Q Q0 Q2 Q3 Q5 Q56 (search for similar items in EconPapers)
Date: 2023
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