Risk of coexisting endometrial carcinoma in case of atypical endometrial ă hyperplasia diagnosed on total hysteroscopic resection

Audrey Pivano, Patrice Crochet, Xavier Carcopino (), Ludovic Cravello, Leon Boubli and Aubert Agostini
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Patrice Crochet: iXFiber SAS - iXFiber SAS
Xavier Carcopino: Service de gynécologie-obstétrique [Hôpital Nord - APHM] - AMU - Aix Marseille Université - APHM - Assistance Publique - Hôpitaux de Marseille - Hôpital Nord [CHU - APHM], IMBE - Institut méditerranéen de biodiversité et d'écologie marine et continentale - AU - Avignon Université - AMU - Aix Marseille Université - Institut de recherche pour le développement [IRD] : UMR237 - CNRS - Centre National de la Recherche Scientifique
Leon Boubli: AMU MED - Aix-Marseille Université - Faculté de médecine - AMU - Aix Marseille Université

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Abstract: Objective: To evaluate the rate of coexisting endometrial carcinoma or ă atypical endometrial hyperplasia (AEH) residue in patients who had a ă total hysteroscopic resection with diagnosis of AEH and without ă suspicious lesions detected during hysteroscopy. ă Study design: This retrospective bicentric study included patients ă diagnosed with AEH on hysteroscopic resection products, and who ă subsequently underwent secondary hysterectomy. Cases of hysteroscopic ă appearance suggesting an endometrial carcinoma were excluded. ă Histopathological results of hysterectomy specimen determined the ă persistence or absence of AEH and the possible presence of coexisting ă endometrial carcinoma. ă Results: Thirty-two patients were selected. Histopathological analysis ă of hysterectomy specimens diagnosed an absence of AEH in 24/32 (75%) ă subjects, an AEH residue in 6/32 (18.8%) subjects and a coexisting ă endometrial carcinoma in 2/32 (6.2%) subjects. ă Conclusion: The risk of missing an endometrial carcinoma in patients ă diagnosed with AEH based on total hysterocopic resection is low when ă there is no suspicious hysteroscopic aspect, but this risk cannot be ă entirely excluded. Total hysteroscopic resection may be a possible ă alternative to hysterectomy in patients with AEH who refuse hysterectomy ă or are a high surgical risk. These patients require a close and long ă term follow-up due to the risks of residual lesion. (C) 2016 Elsevier ă Ireland Ltd. All rights reserved.

Keywords: quality (search for similar items in EconPapers)
Date: 2016-08
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Published in European Journal of Obstetrics & Gynecology and Reproductive Biology, 2016, 203, pp.210-213. ⟨10.1016/j.ejogrb.2016.05.049⟩

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Persistent link: https://EconPapers.repec.org/RePEc:hal:journl:hal-01482366

DOI: 10.1016/j.ejogrb.2016.05.049

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