Benefits of Direct Colposcopic Vision for Optimal LLETZ Procedure: A Prospective Multicenter Study

Lise Preaubert, Jean Gondry (), Julien Mancini (), Julien Chevreau, Gery Lamblin, Anthony Atallah, Vincent Lavoué (), Claire Caradec, Jean-Jacques Baldauf (), Angelique Bryand, Sébastien Henno, Julia Villeret, Aubert Agostini, Serge Douvier, Adelaide Jarniat, Didier Riethmuller, Anne Mendel, Jean-Luc Brun, Hajanarina Rakotomahenina and Xavier Carcopino ()
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Lise Preaubert: Hôpital Nord [CHU - APHM]
Jean Gondry: TMCD2 - Transporteurs membranaires, chimioresistance et drug-design - AMU - Aix Marseille Université - INSERM - Institut National de la Santé et de la Recherche Médicale
Julien Mancini: SESSTIM - U912 INSERM - Aix Marseille Univ - IRD - Sciences Economiques et Sociales de la Santé & Traitement de l'Information Médicale - IRD - Institut de Recherche pour le Développement - AMU - Aix Marseille Université - INSERM - Institut National de la Santé et de la Recherche Médicale, IPC - Institut Paoli-Calmettes - Fédération nationale des Centres de lutte contre le Cancer (FNCLCC), BiosTIC - Biostatistique et technologies de l'information et de la communication (BioSTIC) - [Hôpital de la Timone - APHM] - APHM - Assistance Publique - Hôpitaux de Marseille - TIMONE - Hôpital de la Timone [CHU - APHM]
Gery Lamblin: HFME - Hôpital Femme Mère Enfant [CHU - HCL] - HCL - Hospices Civils de Lyon
Vincent Lavoué: UNS UFR Médecine - Université Nice Sophia Antipolis - Faculté de Médecine - UNS - Université Nice Sophia Antipolis (1965 - 2019)
Jean-Jacques Baldauf: Service de gynécologie–obstétrique - CHU Strasbourg - Centre Hospitalier Universitaire [Strasbourg] - HUS - Les Hôpitaux Universitaires de Strasbourg - Hôpital de Hautepierre [Strasbourg]
Sébastien Henno: Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Pontchaillou]
Serge Douvier: UFR des Sciences de Santé (Université de Bourgogne) - UB - Université de Bourgogne, Service de Gynécologie Obstétrique, Médecine Foetale et Stérilité Conjugale - Chirurgie Gynécologie et Oncologique [CHU de Dijon] - CHU Dijon - Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand
Didier Riethmuller: Service de gynécologie - CHRU Besançon - Centre Hospitalier Régional Universitaire de Besançon - Hôpital Saint-Jacques
Jean-Luc Brun: department of pathology, university hospital, parakou,
Xavier Carcopino: Service de gynécologie-obstétrique [Hôpital Nord - APHM] - AMU - Aix Marseille Université - APHM - Assistance Publique - Hôpitaux de Marseille - Hôpital Nord [CHU - APHM], IMBE - Institut méditerranéen de biodiversité et d'écologie marine et continentale - AU - Avignon Université - AMU - Aix Marseille Université - Institut de recherche pour le développement [IRD] : UMR237 - CNRS - Centre National de la Recherche Scientifique

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Abstract: Objective The aim of the study was to assess whether direct colposcopic ă vision (DCV) of the cervix during large loop excision of the ă transformation zone (LLETZ) is associated with a decrease in the volume ă and dimensions of specimens or affects margin status at histology. ă Materials and Methods A prospective multicenter observational study of ă 216 women who underwent LLETZ for grades 2 and 3 cervical ă intraepithelial neoplasia was conducted. The volume and dimensions ă (circumference, length, and thickness) of the surgical specimens were ă measured before fixation. Data were compared according to the use of ă colposcopy during LLETZ. The following 3 groups were considered: LLETZ ă performed without colposcopy (n = 91), LLETZ performed immediately after ă colposcopy (n = 51), and LLETZ performed under DCV (n = 74). ă Results Patient characteristics were comparable with regard to age, ă parity, history of excision, indication of the procedure, and the size ă of the cervix. We found a significant decrease in all dimensions of the ă specimens obtained under DCV (p

Keywords: Quality; of; Life (search for similar items in EconPapers)
Date: 2016-01
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Published in Journal of Lower Genital Tract Disease, 2016, 20 (1), pp.15-21. ⟨10.1097/LGT.0000000000000156⟩

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Persistent link: https://EconPapers.repec.org/RePEc:hal:journl:hal-01482643

DOI: 10.1097/LGT.0000000000000156

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