MSR133 Integrating Equity and Efficiency in Health Economic Evaluation: Development of Equity-Informed Methodologies in the French Healthcare Context (INEES Project)

Michael Mounié (), Romain Demeulemeester, Benoît Dervaux, Coralie Delettrez, Jennifer Margier, Hassan Serrier, Valéry-Pierre Riche, Christel Castelli, Valérie Clément (), Huiyu Shang, Laurent Molinier, Salah Ghabri, Cyrille Delpierre (), Jerome Wittwer, Pauline Chauvin () and Nadège Costa ()
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Michael Mounié: CHU Toulouse - Centre Hospitalier Universitaire de Toulouse
Romain Demeulemeester: CHU Toulouse - Centre Hospitalier Universitaire de Toulouse
Benoît Dervaux: CHRU Lille - Centre Hospitalier Régional Universitaire [CHU Lille]
Coralie Delettrez: CHRU Lille - Centre Hospitalier Régional Universitaire [CHU Lille]
Jennifer Margier: HCL - Hospices Civils de Lyon
Hassan Serrier: HCL - Hospices Civils de Lyon
Valéry-Pierre Riche: CHU Nantes - Centre Hospitalier Universitaire de Nantes = Nantes University Hospital
Christel Castelli: Clinique Médicale Beausoleil
Valérie Clément: MRE - Montpellier Recherche en Economie - UM - Université de Montpellier
Huiyu Shang: UPCité - Université Paris Cité
Cyrille Delpierre: Equipe EQUITY (CERPOP) - CERPOP - Centre d'Epidémiologie et de Recherche en santé des POPulations - INSERM - Institut National de la Santé et de la Recherche Médicale - EPE UT - Université de Toulouse - Comue de Toulouse - Communauté d'universités et établissements de Toulouse
Pauline Chauvin: LIRAES (URP_ 4470) - Laboratoire Interdisciplinaire de Recherche Appliquée en Economie de la Santé - UPCité - Université Paris Cité, SUAD_SAFIR - SUAD - Sorbonne University Abu Dhabi, SUAD - Sorbonne University Abu Dhabi
Nadège Costa: UEME - Unité d'Evaluation Médico-Economique [CHU Toulouse] - CHU Toulouse - Centre Hospitalier Universitaire de Toulouse

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Abstract: Objectives Traditional economic evaluations in healthcare focus on efficiency but rarely address how health gains are distributed across populations. This project aims to develop, adapt, and test methodologies that explicitly integrate equity into economic evaluations to support fairer health decision-making in the French context. Methods Two complementary approaches will be operationalized: (1) Equity weighting methods, which will adjust cost-effectiveness metrics using weights reflecting population vulnerability; and (2) Distributional Cost-Effectiveness Analysis (DCEA), which will quantify the redistributive impact of health interventions across socioeconomic groups. These methods will be adapted to the French healthcare system, using both aggregated and individual-level data (e.g., from administrative sources and clinical studies). A series of Algorithms and implementation guides will be developed, and the methodologies will be applied to multiple use cases (diabetes, cancer, depression, hearing loss, care coordination). Results The project will generate enhanced cost-effectiveness estimates that incorporate socioeconomic variables. It is expected that applying these equity-informed methods will, in some cases, significantly shift the conclusions of conventional economic evaluations: interventions previously deemed efficient may appear less favorable when considering their distributive impact—and vice versa. The project will also produce practical tools (e.g., equity weighting tables, code libraries, methodological guides) for routine use. These results will help identify interventions most likely to reduce health inequalities while maintaining acceptable levels of efficiency. Conclusions The INEES project will deliver actionable, equity-sensitive economic evaluation tools tailored to the French context. By explicitly integrating both efficiency and equity, this project will contribute to the development of more socially responsive decision-making frameworks, with potential to inform HTA practices, resource allocation, and health policy at the national level.

Date: 2025-12-01
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Published in Value in Health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 2025, 28 (12), pp.S520-S521. ⟨10.1016/j.jval.2025.09.3417⟩

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Persistent link: https://EconPapers.repec.org/RePEc:hal:journl:hal-05483937

DOI: 10.1016/j.jval.2025.09.3417

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