Variable Selection for Nonlinear Cox Regression Model via Deep Learning

Kexuan Li

International Journal of Statistics and Probability, 2025, vol. 12, issue 1, 21

Abstract: Variable selection problem for the nonlinear Cox regression model is considered. In survival analysis, one main objective is to identify the covariates that are associated with the risk of experiencing the event of interest. The Cox proportional hazard model is being used extensively in survival analysis in studying the relationship between survival times and covariates, where the model assumes that the covariate has a log-linear effect on the hazard function. However, this linearity assumption may not be satisfied in practice. In order to extract a representative subset of features, various variable selection approaches have been proposed for survival data under the linear Cox model. However, there exists little literature on variable selection for the nonlinear Cox model. To break this gap, we extend the recently developed deep learning-based variable selection model LassoNet to survival data. Simulations are provided to demonstrate the validity and effectiveness of the proposed method. Finally, we apply the proposed methodology to analyze a real data set on diffuse large B-cell lymphoma.

Date: 2025
References: View references in EconPapers View complete reference list from CitEc
Citations:

Downloads: (external link)
https://ccsenet.org/journal/index.php/ijsp/article/download/0/0/48206/51826 (application/pdf)
https://ccsenet.org/journal/index.php/ijsp/article/view/0/48206 (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:ibn:ijspjl:v:12:y:2025:i:1:p:21

Access Statistics for this article

More articles in International Journal of Statistics and Probability from Canadian Center of Science and Education Contact information at EDIRC.
Bibliographic data for series maintained by Canadian Center of Science and Education ().