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The Neutral Population Model and Bayesian Nonparametrics

Stefano Favaro (), Matteo Ruggiero (), Dario Spanò () and Stephen G. Walker ()

ICER Working Papers - Applied Mathematics Series from ICER - International Centre for Economic Research

Abstract: In this paper a widely-studied model in Population Genetics, the so-called Infinitely- Many-Alleles model with neutral mutation, is reinterpreted in terms of a timedependent Bayesian nonparametric statistical model, where the prior of the model is described by the Neutral Fleming-Viot process. A natural likelihood process is introduced such that every collection of k observations, at each time point, is essentially a vector of i.i.d. samples from the state of the Fleming-Viot process at that time. The dynamic properties of the particle process induced by such a likelihood are studied. The Moran model is derived as the marginal distribution of a timedependent sample induced by such a choice of prior and likelihood. The derivation of all results relies on the transition density of the Neutral Fleming-Viot process and on a new representation for the Dirichlet process.

Keywords: Fleming-Viot process; particle process; Blackwell-MacQueen urn-scheme; transition function; population genetics. (search for similar items in EconPapers)
Pages: 14 pages
Date: 2007-03
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