Optical Techniques for Monitoring Tumour Response to Photodynamic Therapy

Emil Petrescu, Cristina Cartoaje and Mihaela Călin

European Journal of Interdisciplinary Studies, 2009, issue 01

Abstract: Photodynamic therapy is a relatively new method used in malign tumour detection and treatment. The evaluation of the tumour response to this treatment can be made by optical techniques. In the paper below three optical techniques for tumour detection are presented: steady-state, time-resolved and frequency domain. In the steady- state measurements the light irradiation and detection can be either continuous or pulsed but the length of the pulse is long compared to the propagation time of the photons. The reflected light will consist of two parts: the spectral reflection and the diffuse reflectance, but the only one discussed here is the diffuse reflectance and there are two possible entities that can be measured: the total diffuse reflectance or the local diffuse reflectance. Another technique is the time-resolved one, where the transmitted or diffusely-reflected light from a femto- or picoseconds laser pulse is recorded as a function of time and a mathematical model is used to assess the optical properties. In the frequency-domain technique the optical properties are determined from the measurements of phase shift and demodulation of the detected light. These optical methods are non-invasive and nontoxic and present much interest among scientists and physicians as alternative technique for diagnosis and monitoring of cancer treatment.

Keywords: photodynamic therapy; cancer; optical techniques; steady-state technique; time-resolved technique; frequency domain technique (search for similar items in EconPapers)
Date: 2009
References: View complete reference list from CitEc
Citations:

Downloads: (external link)
https://ejist.ro/files/pdf/336.pdf (application/pdf)
https://ejist.ro/abstract/336/Optical-Techniques-f ... dynamic-Therapy.html (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:jis:ejistu:y:2009:i:01:id:336

Access Statistics for this article

More articles in European Journal of Interdisciplinary Studies from Bucharest Economic Academy Contact information at EDIRC.
Bibliographic data for series maintained by Alina Popescu ().