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Toxicodynamic Effects of ‘Red Bull’ Energy Drink in A Randomised Controlled Study on Local Strains of Adult Rabbits Aurita) (Valenciennes, 1847) in Senegalese Coastal Waters

Oluwakemi Iyaniwura Taiwo and Ayoade Abdulfatai Adesokan

Journal of Biology and Life Science, 2018, vol. 9, issue 1, 46-64

Abstract: Increasing reports of anecdotal cases of acute adverse effects associated with the consumption of energy drink have been expressed by international bodies. This has necessitated the need to assess toxicological effects of Red Bull (RB) energy drink in this study. Eighteen adult rabbits were randomly divided into 3 groups of 6 rabbits (3 males and 3 females). Rabbits in groups 1, 2 and 3 (control) received daily oral doses of 23.1 ml RB, 11.5 ml RB and water respectively for 21 days. Venous samples were collected on days 1 (baseline), 14, 21 and 28, and animals were sacrificed on days 21 and 28. Biochemical assessment of liver and renal functions, and muscle activity were carried out by spectrophotometry, in addition to haematological and histological studies. Mortality of 11.1% was recorded, involving 2 female rabbits in group 1. For male rabbits in this group, significant increase (p

Keywords: ‘energy drink’; toxicodynamic; rabbit; histology; adverse effect (search for similar items in EconPapers)
Date: 2018
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