Economic evaluation of disease elimination: An extension to the net-benefit framework and application to human African trypanosomiasis

Marina Antillon, Ching-I Huang, Kat S. Rock and Fabrizio Tediosi
Additional contact information
Marina Antillon: a Epidemiology and Public Health, Swiss Tropical and Public Health Institute, 4123 Allschwil, Switzerland;; b University of Basel, 4001 Basel, Switzerland;
Ching-I Huang: c Zeeman Institute, University of Warwick, Coventry CV4 7AL, United Kingdom;; d Mathematics Institute, University of Warwick, Coventry CV4 7AL, United Kingdom
Kat S. Rock: c Zeeman Institute, University of Warwick, Coventry CV4 7AL, United Kingdom;; d Mathematics Institute, University of Warwick, Coventry CV4 7AL, United Kingdom
Fabrizio Tediosi: a Epidemiology and Public Health, Swiss Tropical and Public Health Institute, 4123 Allschwil, Switzerland;; b University of Basel, 4001 Basel, Switzerland;

Proceedings of the National Academy of Sciences, 2021, vol. 118, issue 50, e2026797118

Abstract: While the health economic implications of disease elimination have been discussed before, the combination of uncertainty, cost effectiveness, and elimination has not been tackled before. We propose a modification to the net-benefit framework to explicitly consider the implications of switching from an optimal strategy, in terms of cost-per-burden averted, to a strategy with a higher likelihood of meeting the global target of elimination. The modification proposed yields a methodology to quantify the efficiency of elimination and to aid discussions among stakeholders with different objectives. We apply our method to strategies against human African trypanosomiasis in three settings, but this method is flexible enough that it can be applied directly to any simulation-based studies of disease elimination efforts.

Keywords: eradication; elimination; economic evaluation; mathematical modeling (search for similar items in EconPapers)
Date: 2021
References: Add references at CitEc
Citations: View citations in EconPapers (1)

Downloads: (external link)
http://www.pnas.org/content/118/50/e2026797118.full (application/pdf)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nas:journl:v:118:y:2021:p:e2026797118

Access Statistics for this article

More articles in Proceedings of the National Academy of Sciences from Proceedings of the National Academy of Sciences
Bibliographic data for series maintained by PNAS Product Team ().