Immune features are associated with response to neoadjuvant chemo-immunotherapy for muscle-invasive bladder cancer

Wolfgang Beckabir, Mi Zhou, Jin Seok Lee, Steven P. Vensko, Mark G. Woodcock, Hsing-Hui Wang, Sara E. Wobker, Gatphan Atassi, Alec D. Wilkinson, Kenneth Fowler, Leah M. Flick, Jeffrey S. Damrauer, Michael R. Harrison, Karen P. McKinnon, Tracy L. Rose, Matthew I. Milowsky, Jonathan S. Serody (), William Y. Kim () and Benjamin G. Vincent ()
Additional contact information
Wolfgang Beckabir: University of North Carolina at Chapel Hill
Mi Zhou: University of North Carolina at Chapel Hill
Jin Seok Lee: University of North Carolina at Chapel Hill
Steven P. Vensko: University of North Carolina at Chapel Hill
Mark G. Woodcock: University of North Carolina at Chapel Hill
Hsing-Hui Wang: University of North Carolina at Chapel Hill
Sara E. Wobker: University of North Carolina at Chapel Hill
Gatphan Atassi: University of North Carolina at Chapel Hill
Alec D. Wilkinson: University of North Carolina at Chapel Hill
Kenneth Fowler: University of North Carolina at Chapel Hill
Leah M. Flick: University of North Carolina at Chapel Hill
Jeffrey S. Damrauer: University of North Carolina at Chapel Hill
Michael R. Harrison: Duke University
Karen P. McKinnon: University of North Carolina at Chapel Hill
Tracy L. Rose: University of North Carolina at Chapel Hill
Matthew I. Milowsky: University of North Carolina at Chapel Hill
Jonathan S. Serody: University of North Carolina at Chapel Hill
William Y. Kim: University of North Carolina at Chapel Hill
Benjamin G. Vincent: University of North Carolina at Chapel Hill

Nature Communications, 2024, vol. 15, issue 1, 1-14

Abstract: Abstract Neoadjuvant cisplatin-based chemotherapy is standard of care for muscle-invasive bladder cancer (MIBC). Immune checkpoint inhibition (ICI) alone, and ICI in combination with chemotherapy, have demonstrated promising pathologic response (

Date: 2024
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DOI: 10.1038/s41467-024-48480-1

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