Dynamic rigidity changes enable rapid cell migration on soft substrates

Jiapeng Yang, Yu Zhang, Shuo Wang, Peng Wang, Liang Dong, Luofei Li, Yuanqi Cheng, Xiaoyu Huang, Bin Xue, Wei Wang, Chunping Jiang (), Xiaosong Gu, Yi Cao () and Qiang Wei ()
Additional contact information
Jiapeng Yang: Jinan Microecological Biomedicine Shandong Laboratory
Yu Zhang: Jinan Microecological Biomedicine Shandong Laboratory
Shuo Wang: Nanjing University
Peng Wang: Sichuan University
Liang Dong: Nanjing University
Luofei Li: Nanjing University
Yuanqi Cheng: Nanjing University
Xiaoyu Huang: Nanjing University
Bin Xue: Nanjing University
Wei Wang: Nanjing University
Chunping Jiang: Jinan Microecological Biomedicine Shandong Laboratory
Xiaosong Gu: Jinan Microecological Biomedicine Shandong Laboratory
Yi Cao: Jinan Microecological Biomedicine Shandong Laboratory
Qiang Wei: Sichuan University

Nature Communications, 2025, vol. 16, issue 1, 1-17

Abstract: Abstract Cell migration is crucial in various biological processes, regulated by surrounding rigidity. Studies under static conditions suggest migration favors rigid substrates, as softer substrates (

Date: 2025
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DOI: 10.1038/s41467-025-63854-9

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