Impact of a phased transition model on Advanced HIV Disease outcomes: A pre- and post-implementation evaluation study in Malawi

Thulani Maphosa, Rhoderick Machekano, Lise Denoeud Ndam, Lucky Makonokaya, Lloyd Chilikutali, Louiser Upile Kalitera, Eddington Matiya, Allan Mayi, Reuben Musarandega, Bilal Wilson Matola, Aida Yemane Berhan, Allan Ahimbisibwe and Appolinaire Tiam

PLOS Global Public Health, 2026, vol. 6, issue 10, 1-15

Abstract: To promote sustainability and strengthen national ownership of Advanced HIV Disease (AHD) services, a transition was implemented across 22 health facilities in Central Malawi. This transition involved shifting responsibility for key AHD program elements from partner-led implementation to full Ministry of Health (MoH) leadership. This evaluation assessed the impact of this transition on diagnostic coverage, TB preventive therapy (TPT) uptake, and 12-month survival outcomes. A retrospective cohort study included all children and adults enrolled in AHD care during the pre-MoH transition (January 2020–December 2021) and post-MoH transition (January 2023–December 2024) periods. Eligibility was defined by national AHD criteria: CD4 count

Date: 2026
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pgph00:0006348

DOI: 10.1371/journal.pgph.0006348

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