Risk Stratification by Self-Measured Home Blood Pressure across Categories of Conventional Blood Pressure: A Participant-Level Meta-Analysis

Kei Asayama, Lutgarde Thijs, Jana Brguljan-Hitij, Teemu J Niiranen, Atsushi Hozawa, José Boggia, Lucas S Aparicio, Azusa Hara, Jouni K Johansson, Takayoshi Ohkubo, Christophe Tzourio, George S Stergiou, Edgardo Sandoya, Ichiro Tsuji, Antti M Jula, Yutaka Imai, Jan A Staessen and for the International Database of Home Blood Pressure in Relation to Cardiovascular Outcome (IDHOCO) Investigators

PLOS Medicine, 2014, vol. 11, issue 1, 1-16

Abstract: : Jan Staessen and colleagues compare the risk of cardiovascular, cardiac, or cerebrovascular events in patients with elevated office blood pressure vs. self-measured home blood pressure. Background: The Global Burden of Diseases Study 2010 reported that hypertension is worldwide the leading risk factor for cardiovascular disease, causing 9.4 million deaths annually. We examined to what extent self-measurement of home blood pressure (HBP) refines risk stratification across increasing categories of conventional blood pressure (CBP). Methods and Findings: This meta-analysis included 5,008 individuals randomly recruited from five populations (56.6% women; mean age, 57.1 y). All were not treated with antihypertensive drugs. In multivariable analyses, hazard ratios (HRs) associated with 10-mm Hg increases in systolic HBP were computed across CBP categories, using the following systolic/diastolic CBP thresholds (in mm Hg): optimal,

Date: 2014
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pmed00:1001591

DOI: 10.1371/journal.pmed.1001591

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