Association between ambient air pollution and daily hospital admissions for ischemic stroke: A nationwide time-series analysis

Yaohua Tian, Hui Liu, Zuolin Zhao, Xiao Xiang, Man Li, Juan Juan, Jing Song, Yaying Cao, Xiaowen Wang, Libo Chen, Chen Wei, Yonghua Hu and Pei Gao

PLOS Medicine, 2018, vol. 15, issue 10, 1-16

Abstract: Background: Evidence of the short-term effects of ambient air pollution on the risk of ischemic stroke in low- and middle-income countries is limited and inconsistent. We aimed to examine the associations between air pollution and daily hospital admissions for ischemic stroke in China. Methods and findings: We identified hospital admissions for ischemic stroke in 2014–2016 from the national database covering up to 0.28 billion people who received Urban Employee Basic Medical Insurance (UEBMI) in China. We examined the associations between air pollution and daily ischemic stroke admission using a two-stage method. Poisson time-series regression models were firstly fitted to estimate the effects of air pollution in each city. Random-effects meta-analyses were then conducted to combine the estimates. Meta-regression models were applied to explore potential effect modifiers. More than 2 million hospital admissions for ischemic stroke were identified in 172 cities in China. In single-pollutant models, increases of 10 μg/m3 in particulate matter with aerodynamic diameter

Date: 2018
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pmed00:1002668

DOI: 10.1371/journal.pmed.1002668

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