Prognostic value of cervical length for spontaneous preterm birth in asymptomatic women with singleton pregnancy: An individual participant data meta-analysis

Hughes, Kelly; Nguyen, David; Aberoumand, Mason; Ford, Heather; Clarke, Erin; Lopez, Nuria Banos; Dziadosz, Margaret; Fischer, Richard; Souza, Renato T; Cecatti, Jose Guilherme; Orzechowski, Kelly; Olson-Chen, Courtney; Peixoto, Alberto Borges; Phupong, Vorapong; Rosenbloom, Joshua; Son, Moeun; Souka, Athena; Du, Liu; Esplin, Michael Sean; Granese, Roberta; Gupta, Simi; Kazemier, Brenda; Kindinger, Lindsay; Kuusela, Pihla; Van der Ven, Jeanine; Weitzner, Omer; Minis, Evelyn; Llobet, Alba Farras; Frey, Heather; Bagga, Rashmi; Mishra, Siddhidatri; Patberg, Elizabeth; Bennett, Philip; Hall, Megan; Shennan, Andrew; Brennecke, Shaun; Thangaratinam, Shakila; Seidler, Anna Lene; Mol, Ben Willem; Wang, Rui

Prognostic value of cervical length for spontaneous preterm birth in asymptomatic women with singleton pregnancy: An individual participant data meta-analysis

Kelly Hughes, David Nguyen, Mason Aberoumand, Heather Ford, Erin Clarke, Nuria Banos Lopez, Margaret Dziadosz, Richard Fischer, Renato T Souza, Jose Guilherme Cecatti, Kelly Orzechowski, Courtney Olson-Chen, Alberto Borges Peixoto, Vorapong Phupong, Joshua Rosenbloom, Moeun Son, Athena Souka, Liu Du, Michael Sean Esplin, Roberta Granese, Simi Gupta, Brenda Kazemier, Lindsay Kindinger, Pihla Kuusela, Jeanine Van der Ven, Omer Weitzner, Evelyn Minis, Alba Farras Llobet, Heather Frey, Rashmi Bagga, Siddhidatri Mishra, Elizabeth Patberg, Philip Bennett, Megan Hall, Andrew Shennan, Shaun Brennecke, Shakila Thangaratinam, Anna Lene Seidler, Ben Willem Mol and Rui Wang

PLOS Medicine, 2026, vol. 23, issue 6, 1-22

Abstract: Background: Spontaneous preterm birth (SPTB) is the leading cause of perinatal and early childhood mortality worldwide. Studies have generally suggested that mid-trimester transvaginal sonographic cervical length 90,000 singleton pregnancies, Kelly Hughes and colleagues quantify the prognostic value of mid-trimester cervical length for spontaneous preterm birth in asymptomatic women with singleton pregnancy, and assess other factors which may modify this association.

Date: 2026
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pmed00:1004653

DOI: 10.1371/journal.pmed.1004653

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