Risk Factors for Disseminated Histoplasmosis in a Cohort of HIV-Infected Patients in French Guiana

Mathieu Nacher, Antoine Adenis, Denis Blanchet, Vincent Vantilcke, Magalie Demar, Célia Basurko, Emilie Gaubert-Maréchal, Julie Dufour, Christine Aznar, Bernard Carme and Pierre Couppié

PLOS Neglected Tropical Diseases, 2014, vol. 8, issue 1, 1-7

Abstract: Disseminated histoplasmosis is the first AIDS-defining infection in French Guiana. A retrospective cohort study studied predictive factors of disseminated histoplasmosis in HIV-infected patients between 1996 and 2008. Cox proportional hazards models were used. The variables studied were age, sex, last CD4/CD8 count, CD4 nadir, herpes or pneumocystosis, cotrimoxazole and fluconazole use, antiretroviral treatment and the notion of recent initiation of HAART. A total of 1404 patients were followed for 6833 person-years. The variables independently associated with increased incidence of disseminated histoplasmosis were CD4 count

Date: 2014
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pntd00:0002638

DOI: 10.1371/journal.pntd.0002638

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