Cross-Sectional Surveys of the Prevalence of Follicular Trachoma and Trichiasis in The Gambia: Has Elimination Been Reached?

Sarah E Burr, Ansumana Sillah, Anselme S Sanou, Anita C Wadagni, John Hart, Emma M Harding-Esch, Sarjo Kanyi and Robin L Bailey

PLOS Neglected Tropical Diseases, 2016, vol. 10, issue 9, 1-9

Abstract: Background: The Gambia’s National Eye Health Programme has made a concerted effort to reduce the prevalence of trachoma. The present study had two objectives. The first was to conduct surveillance following mass drug administrations to determine whether The Gambia has reached the World Health Organization’s (WHO) criteria for trachoma elimination, namely a prevalence of trachomatous inflammation—follicular (TF) of less than 5% in children aged 1 to 9 years. The second was to determine the prevalence of trichiasis (TT) cases unknown to the programme and evaluate whether these meet the WHO criteria of less than 0.1% in the total population. Methodology/Principal Findings: Three cross-sectional surveys were conducted between 2011 and 2013 to determine the prevalence of TF and TT in each of nine surveillance zones. Each zone was of similar size, with a population of 60,000 to 90,000, once urban settlements were excluded. Trachoma grading was carried out according to the WHO’s simplified trachoma grading system. The prevalence of TF in children aged 1 to 9 years was less than 5% in each surveillance zone at each of the three surveys. The prevalence of TT cases varied by zone from 0 to 1.7% of adults greater than 14 years while the prevalence of TT cases unknown to the country’s National Eye Health Programme was estimated at 0.15% total population. Conclusions/Significance: The Gambia has reached the elimination threshold for TF in children. Further work is needed to bring the number of unknown TT cases below the elimination threshold. Author Summary: Trachoma, the world’s leading infectious cause of blindness, is caused by ocular infection with the bacterium Chlamydia trachomatis. The Gambia, situated in West Africa, has implemented all facets of the World Health Organization-recommended SAFE strategy for trachoma control including surgery to correct the in-turning of eyelashes (trichiasis), mass drug administration with antibiotics, promotion of facial hygiene and environmental improvements. In 2011, The Gambia’s National Eye Health Programme began three years of rolling surveys to determine the prevalence of trachoma in the country and to evaluate whether trachoma elimination has been reached. The results suggest the country has reached the elimination threshold for trachoma in children (less than 5% prevalence) but that more work needs to be done to reduce the prevalence of trichiasis in adults.

Date: 2016
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pntd00:0004906

DOI: 10.1371/journal.pntd.0004906

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