Scabies and risk of skin sores in remote Australian Aboriginal communities: A self-controlled case series study

Phyo Thu Zar Aung, Will Cuningham, Kerry Hwang, Ross M Andrews, Jonathan R Carapetis, Therese Kearns, Danielle Clucas, Jodie McVernon, Julie Ann Simpson, Steven YC Tong and Patricia Therese Campbell

PLOS Neglected Tropical Diseases, 2018, vol. 12, issue 7, 1-11

Abstract: Background: Skin sores caused by Group A streptococcus (GAS) infection are a major public health problem in remote Aboriginal communities. Skin sores are often associated with scabies, which is evident in scabies intervention programs where a significant reduction of skin sores is seen after focusing solely on scabies control. Our study quantifies the strength of association between skin sores and scabies among Aboriginal children from the East Arnhem region in the Northern Territory. Methods and results: Pre-existing datasets from three published studies, which were conducted as part of the East Arnhem Healthy Skin Project (EAHSP), were analysed. Aboriginal children were followed from birth up to 4.5 years of age. Self-controlled case series design was used to determine the risks, within individuals, of developing skin sores when infected with scabies versus when there was no scabies infection. Participants were 11.9 times more likely to develop skin sores when infected with scabies compared with times when no scabies infection was evident (Incidence Rate Ratio (IRR) 11.9; 95% CI 10.3–13.7; p 1 year (IRR 0.8; 95% CI 0.7–0.9). Conclusion: The association between scabies and skin sores is highly significant and indicates a causal relationship. The public health importance of scabies in northern Australia is underappreciated and a concerted approach is required to recognise and eliminate scabies as an important precursor of skin sores. Author summary: Skin sores, also known as impetigo, are highly contagious bacterial skin infections, which are found commonly in school children and occasionally in adults. Skin sores are prevalent in disadvantaged or resource-poor settings. In Australia, about two thirds of Aboriginal children suffer from skin sores by their first birthday. If untreated or treated poorly, skin sores can eventually cause heart and kidney problems. It is also believed that scabies, another common skin infection in Aboriginal children, can increase the risk of developing skin sores by allowing the bacteria to enter the skin more easily through breaks in the skin. Our research explored the following: if scabies is a risk factor for skin sores then what is the strength of the association between the two conditions.

Date: 2018
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pntd00:0006668

DOI: 10.1371/journal.pntd.0006668

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