Estimated incidence and Prevalence of noma in north central Nigeria, 2010–2018: A retrospective study

Seidu A Bello, John A Adeoye, Ifeoluwa Oketade and Oladimeji A Akadiri

PLOS Neglected Tropical Diseases, 2019, vol. 13, issue 7, 1-12

Abstract: Background: Noma is a spreading and fulminant disease believed to be native to Sub-Saharan Africa over the last decade and associated with low socioeconomic status of citizens of the region. Within this noma belt, most epidemiological reports regarding the disease have emanated from the north western region of Nigeria. However, our indigenous surgical mission encountered a substantial number of cases of noma and post-noma defects noteworthy of epidemiological representation across north central Nigeria. Methods: All noma cases encountered within the 8-year study period were included and divided based on clinical signs into acute and sequelae groups. Incidence estimation was based on acute/recently active cases and was calculated using the statistical method proposed by the WHO Oral Health Unit (1994). Period prevalence of noma was calculated considering the population at risk in the zone. Findings: A total of 78 subjects were included in the study with age ranging from 2–75 years. Twelve subjects (15.4%) presented with acute disease while 66 (84.6%) had various forms of post-noma defects. The estimated incidence of noma in the north central zone was 8.3 per 100000 with a range of 4.1–17.9 per 100000 across various states. Period prevalence of noma which incorporated all cases seen within the study period was 1.6 per 100000 population at risk. Conclusion: Although noma may be more prevalent in the north western region of Nigeria, substantial number of cases occurs within the north central zone which calls for deliberate public awareness campaign on disease risk factors and prevention, and education of primary health-care providers. Author summary: Noma, a devouring disease of the orofacial complex, is commonly associated with poverty and impoverished regions of the world especially Sub-Saharan Africa termed the noma belt region of the world. With more reports advocating for full inclusion of noma in the WHO Neglected Tropical Diseases (NTDs) program, the apparent neglect of the disease in north central Nigeria compared to other sub-regions is worrisome as the disease burden in the sub-region has not been reported till date. In this light, a retrospective, cross-sectional survey was conducted to provide epidemiological representation to the cases encountered within an eight-year period by the Cleft and Facial Deformity Foundation (CFDF), an indigenous surgical mission. The incidence of noma was estimated using methods recommended by WHO while the period prevalence was calculated considering the population living below poverty line in the sub-region. This study extrapolates an incidence of 8.3 cases per 100000 and a period prevalence of 1.6 per 100000 persons at risk. Notable is the finding that most individuals encountered were above thirty years of age and suffered varying degree of facial disfigurement consequent to acute noma disease experienced in their childhood/early adolescence. Therefore, we advocate public awareness on the disease risk factors and prevention within the sub-region as well as training of primary health personnel on disease identification, primary care and nearest referral centres. We also identify the need to bolster the efforts of existing health facilities and indigenous surgical missions in the management and rehabilitation of noma cases and survivors.

Date: 2019
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pntd00:0007574

DOI: 10.1371/journal.pntd.0007574

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