Efficacy and safety of single-dose 40 mg/kg oral praziquantel in the treatment of schistosomiasis in preschool-age versus school-age children: An individual participant data meta-analysis

Piero L Olliaro, Jean T Coulibaly, Amadou Garba, Christine Halleux, Jennifer Keiser, Charles H King, Francisca Mutapi, Eliézer K N’Goran, Giovanna Raso, Alexandra U Scherrer, José Carlos Sousa-Figueiredo, Katarina Stete, Jürg Utzinger and Michel T Vaillant

PLOS Neglected Tropical Diseases, 2020, vol. 14, issue 6, 1-23

Abstract: Background: Better knowledge of the efficacy and safety of single-dose 40 mg/kg oral praziquantel in preschool-age children is required, should preventive chemotherapy programs for schistosomiasis be expanded to include this age group. Methodology: We analyzed individual participant-level data from 16 studies (13 single-arm or cohort studies and three randomized trials), amounting to 683 preschool-age children (aged

Date: 2020
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pntd00:0008277

DOI: 10.1371/journal.pntd.0008277

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