Comprehensive microRNA Analysis Identifies miR-24 and miR-125a-5p as Plasma Biomarkers for Rheumatoid Arthritis
Koichi Murata,
Moritoshi Furu,
Hiroyuki Yoshitomi,
Masahiro Ishikawa,
Hideyuki Shibuya,
Motomu Hashimoto,
Yoshitaka Imura,
Takao Fujii,
Hiromu Ito,
Tsuneyo Mimori and
Shuichi Matsuda
PLOS ONE, 2013, vol. 8, issue 7, 1-10
Abstract:
MicroRNAs (miRNAs) are present in human plasma and known as a non-invasive biomarker for cancer detection. Our study was designed to identify plasma miRNAs specific for rheumatoid arthritis (RA) by a comprehensive array approach. We performed a systematic, array-based miRNA analysis on plasma samples from three RA patients and three healthy controls (HCs). Plasma miRNAs with more than four times change or with significant (P
Date: 2013
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0069118
DOI: 10.1371/journal.pone.0069118
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