Structural Insights into RbmA, a Biofilm Scaffolding Protein of V. Cholerae
Manuel Maestre-Reyna,
Wen-Jin Wu and
Andrew H-J Wang
PLOS ONE, 2013, vol. 8, issue 12, 1-
Abstract:
V. cholerae can form sessile biofilms associated with abiotic surfaces, cyanobacteria, zoo-plankton, mollusks, or crustaceans. Along with the vibrio polysaccharide, secreted proteins of the rbm gene cluster are key to the biofilm ultrastructure. Here we provide a thorough structural characterization of RbmA, a protein involved in mediating cell-cell and cell-biofilm contacts. We correlate our structural findings with initial ligand specificity screening results, NMR protein-ligand interaction analysis, and complement our results with a full biocomputational study.
Date: 2013
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0082458
DOI: 10.1371/journal.pone.0082458
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