A Procalcitonin-Based Algorithm to Guide Antibiotic Therapy in Secondary Peritonitis following Emergency Surgery: A Prospective Study with Propensity Score Matching Analysis

Ting-Shuo Huang, Shie-Shian Huang, Yu-Chiau Shyu, Chun-Hui Lee, Shyh-Chuan Jwo, Pei-Jer Chen and Huang-Yang Chen

PLOS ONE, 2014, vol. 9, issue 3, 1-7

Abstract: Background: Procalcitonin (PCT)-based algorithms have been used to guide antibiotic therapy in several clinical settings. However, evidence supporting PCT-based algorithms for secondary peritonitis after emergency surgery is scanty. In this study, we aimed to investigate whether a PCT-based algorithm could safely reduce antibiotic exposure in this population. Methods/Principal Findings: From April 2012 to March 2013, patients that had secondary peritonitis diagnosed at the emergency department and underwent emergency surgery were screened for eligibility. PCT levels were obtained pre-operatively, on post-operative days 1, 3, 5, and 7, and on subsequent days if needed. Antibiotics were discontinued if PCT was

Date: 2014
References: View complete reference list from CitEc
Citations:

Downloads: (external link)
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0090539 (text/html)
https://journals.plos.org/plosone/article/file?id= ... 90539&type=printable (application/pdf)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0090539

DOI: 10.1371/journal.pone.0090539

Access Statistics for this article

More articles in PLOS ONE from Public Library of Science
Bibliographic data for series maintained by plosone ().