Serum Thyroid-Stimulating Hormone and Anti-Thyroglobulin Antibody Are Independently Associated with Lesions in Spinal Cord in Central Nervous System Demyelinating Diseases

Youming Long, Yangbo Zheng, Mengyu Chen, Bin Zhang, Cong Gao, Fulan Shan, Ning Yang and Yongxiang Fan

PLOS ONE, 2014, vol. 9, issue 8, 1-9

Abstract: Transverse myelitis (TM) is associated with neuromyelitis optica (NMO) and multiple sclerosis (MS). Early recognition of useful parameters may be helpful to distinguish their difference. This retrospective study analyzed thyroid parameters from 243 serum samples (relapse = 128; remission = 115) of 178 patients with demyelinating diseases (NMO, n = 25; TM, n = 48; MS, n = 105). The relationship between thyroid and clinical parameters was analyzed. Patients with NMO and TM had a higher frequency of abnormal thyroid-stimulating hormone (TSH), anti-thyroglobulin antibodies (TG-Ab), and antithyroid peroxidase antibody (TPO-Ab) than MS patients (p

Date: 2014
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0100672

DOI: 10.1371/journal.pone.0100672

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