Moxibustion Treatment for Knee Osteoarthritis: A Multi-Centre, Non-Blinded, Randomised Controlled Trial on the Effectiveness and Safety of the Moxibustion Treatment versus Usual Care in Knee Osteoarthritis Patients

Tae-Hun Kim, Kun Hyung Kim, Jung Won Kang, MinHee Lee, Kyung-Won Kang, Jung Eun Kim, Joo-Hee Kim, Seunghoon Lee, Mi-Suk Shin, So-Young Jung, Ae-Ran Kim, Hyo-Ju Park, Hee-Jung Jung, Ho Sueb Song, Hyeong Jun Kim, Jin-Bong Choi, Kwon Eui Hong and Sun-Mi Choi

PLOS ONE, 2014, vol. 9, issue 7, 1-8

Abstract: Introduction: This study tested the effectiveness of moxibustion on pain and function in chronic knee osteoarthritis (KOA) and evaluated safety. Methods: A multi-centre, non-blinded, parallel-group, randomised controlled trial compared moxibustion with usual care (UC) in KOA. 212 South Korean patients aged 40–70 were recruited from 2011–12, stratified by mild (Kellgren/Lawrence scale grades 0/1) and moderate-severe KOA (grades 2/3/4), and randomly allocated to moxibustion or UC for four weeks. Moxibustion involved burning mugwort devices over acupuncture and Ashi points in affected knee(s). UC was allowed. Korean Western Ontario and McMaster Universities Questionnaire (K-WOMAC), Short Form 36 Health Survey (SF-36v2), Beck Depression Inventory (BDI), physical performance test, pain numeric rating scale (NRS) and adverse events were evaluated at 5 and 13 weeks. K-WOMAC global score at 5 weeks was the primary outcome. Results: 102 patients (73 mild, 29 moderate-severe) were allocated to moxibustion, 110 (77 mild, 33 moderate-severe) to UC. K-WOMAC global score (moxibustion 25.42+/−SD 19.26, UC 33.60+/−17.91, p

Date: 2014
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0101973

DOI: 10.1371/journal.pone.0101973

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