Pilot Quasi-Randomized Controlled Study of Herbal Medicine Hochuekkito as an Adjunct to Conventional Treatment for Progressed Pulmonary Mycobacterium avium Complex Disease

Yasunori Enomoto, Eri Hagiwara, Shigeru Komatsu, Ryuichi Nishihira, Tomohisa Baba, Hideya Kitamura, Akimasa Sekine, Atsuhito Nakazawa and Takashi Ogura

PLOS ONE, 2014, vol. 9, issue 8, 1-8

Abstract: Introduction: Hochuekkito, a traditional herbal medicine, is occasionally prescribed in Japan to treat patients with a poor general condition. We aimed to examine whether this medicine was beneficial and tolerable for patients with progressed pulmonary Mycobacterium avium complex (MAC) disease. Methods: This pilot open-label quasi-randomized controlled trial enrolled 18 patients with progressed pulmonary MAC disease who had initiated antimycobacterial treatment over one year ago but were persistently culture-positive or intolerant. All patients continued their baseline treatment regimens with (n = 9) or without (n = 9) oral Hochuekkito for 24 weeks. Results: Baseline characteristics were generally similar between the groups. Most patients were elderly (median age 70 years), female, had a low body mass index (

Date: 2014
References: View complete reference list from CitEc
Citations:

Downloads: (external link)
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0104411 (text/html)
https://journals.plos.org/plosone/article/file?id= ... 04411&type=printable (application/pdf)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0104411

DOI: 10.1371/journal.pone.0104411

Access Statistics for this article

More articles in PLOS ONE from Public Library of Science
Bibliographic data for series maintained by plosone ().