Burden of Diabetes Mellitus Estimated with a Longitudinal Population-Based Study Using Administrative Databases

Luciana Scalone, Giancarlo Cesana, Gianluca Furneri, Roberta Ciampichini, Paolo Beck-Peccoz, Virginio Chiodini, Silvia Mangioni, Emanuela Orsi, Carla Fornari and Lorenzo Giovanni Mantovani

PLOS ONE, 2014, vol. 9, issue 12, 1-11

Abstract: Objective: To assess the epidemiologic and economic burden of diabetes mellitus (DM) from a longitudinal population-based study. Research Design and Methods: Lombardy Region includes 9.9 million individuals. Its DM population was identified through a data warehouse (DENALI), which matches with a probabilistic linkage demographic, clinical and economic data of different Healthcare Administrative databases. All individuals, who, during the year 2000 had an hospital discharge with a IDC-9 CM code 250.XX, and/or two consecutive prescriptions of drugs for diabetes (ATC code A10XXXX) within one year, and/or an exemption from co-payment healthcare costs specific for DM, were selected and followed up to 9 years. We calculated prevalence, mortality and healthcare costs (hospitalizations, drugs and outpatient examinations/visits) from the National Health Service’s perspective. Results: We identified 312,223 eligible subjects. The study population (51% male) had a mean age of 66 (from 0.03 to 105.12) years at the index date. Prevalence ranged from 0.4% among subjects aged ≤45 years to 10.1% among those >85 years old. Overall 43.4 deaths per 1,000 patients per year were estimated, significantly (p

Date: 2014
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0113741

DOI: 10.1371/journal.pone.0113741

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