Age-Dependent Morphologic Alterations in the Outer Retinal and Choroidal Thicknesses Using Swept Source Optical Coherence Tomography

Ichiro Maruko, Hisaya Arakawa, Hideki Koizumi, Reiko Izumi, Hiromi Sunagawa and Tomohiro Iida

PLOS ONE, 2016, vol. 11, issue 7, 1-8

Abstract: Purpose: To evaluate the age-dependent morphologic alterations in the outer retina and choroid at the macula using swept-source optical coherence tomography (OCT). Methods: Thirty eyes (30 normal subjects; average age, 49 years) were examined; five (age range, third-eighth decades of life) had refractive errors of ±2 diopters or less and no fundus abnormalities. An Early Treatment Diabetic Retinopathy Study (ETDRS) map of the outer retinal and choroidal thickness was constructed using swept-source OCT. The outer retinal and choroidal segmentation lines were drawn automatically, partially manually, within 6 millimeters of the macula. Results: The mean outer retinal and choroidal thicknesses in the 6-millimeter-diameter circle were 145±13 and 236±68 microns, respectively. The choroidal thickness and age were negatively (r = -0.66, P

Date: 2016
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0159439

DOI: 10.1371/journal.pone.0159439

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