Heart rate variability among women undergoing in vitro fertilization treatment: Its predictive ability for pregnancy

Meng-Hsing Wu, Pei-Fang Su, Kuan-Ya Chen, Tung-Hee Tie, Hsu-Cheng Ke, Hau Chen, Yu-Chi Su, Yu-Chen Su and Huang-Tz Ou

PLOS ONE, 2018, vol. 13, issue 3, 1-12

Abstract: Objective: This study aimed to assess predictive ability of heart rate variability (HRV) for pregnancy outcomes with in vitro fertilization (IVF) treatment. Research design and method: A total of 180 women with 261 cycles of IVF and 211 embryo transfers (ETs) were analyzed. HRV was measured at four times during IVF treatment: the first date of menstruation, r-HCG (Ovidrel) administration, and before and after ET. Pregnancy indicators included chemical pregnancy, ongoing pregnancy (> 10 weeks), and live birth (pregnancy > 24 weeks). Mixed effect models were applied to identify predictors for IVF pregnancy. The area under the receiver operating characteristic curve (AUC) was used to assess prediction models for pregnancy. Results: The HRV values increased during IVF treatment and then decreased after ET. The trend of changes in HRV values during IVF treatment was significant among patients with chemical pregnancy (p

Date: 2018
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0193899

DOI: 10.1371/journal.pone.0193899

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