Is body mass index associated with outcomes of mechanically ventilated adult patients in intensive critical units? A systematic review and meta-analysis

Yonghua Zhao, Zhiqiang Li, Tao Yang, Meiping Wang and Xiuming Xi

PLOS ONE, 2018, vol. 13, issue 6, 1-15

Abstract: Background: Obesity paradox refers to lower mortality in subjects with higher body mass index (BMI), and has been documented under a variety of condition. However, whether obesity paradox exists in adults requiring mechanical ventilation in intensive critical units (ICU) remains controversial. Methods: MEDLINE, EMBASE, China Biology Medicine disc (CBM) and CINAHL electronic databases were searched from the earliest available date to July 2017, using the following search terms: “body weight”, “body mass index”, “overweight” or “obesity” and “ventilator”, “mechanically ventilated”, “mechanical ventilation”, without language restriction. Subjects were divided into the following categories based on BMI (kg/m2): underweight, 40 kg/m2. The primary outcome was mortality, and included ICU mortality, hospital mortality, short-term mortality (

Date: 2018
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0198669

DOI: 10.1371/journal.pone.0198669

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