Urbanization as a risk factor for aortic stiffness in a cohort in India

Laura Corlin, Kevin J Lane, Jahnavi Sunderarajan, Kenneth K H Chui, Harivanza Vijayakumar, Lawrence Krakoff, Anbarasi Chandrasekaran, Sadagopan Thanikachalam, Doug Brugge and Mohan Thanikachalam

PLOS ONE, 2018, vol. 13, issue 8, 1-14

Abstract: Urbanization is associated with higher prevalence of cardiovascular disease worldwide. Aortic stiffness, as measured by carotid-femoral pulse wave velocity is a validated predictor of cardiovascular disease. Our objective was to determine the association between urbanization and carotid-femoral pulse wave velocity. The analysis included 6166 participants enrolled in an ongoing population-based study (mean age 42 years; 58% female) who live in an 80 × 80 km region of southern India. Multiple measures of urbanization were used and compared: 1) census designations, 2) satellite derived land cover (crops, grass, shrubs or trees as rural; built-up areas as urban), and 3) distance categories based on proximity to an urban center. The association between urbanization and carotid-femoral pulse wave velocity was tested in sex-stratified linear regression models. People residing in urban areas had significantly (p

Date: 2018
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0201036

DOI: 10.1371/journal.pone.0201036

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