RV adaptation to increased afterload in congenital heart disease and pulmonary hypertension

Mieke M P Driessen, Tim Leiner, Gertjan Tj Sieswerda, Arie P J van Dijk, Marco C Post, Mark K Friedberg, Luc Mertens, Pieter A Doevendans, Repke J Snijder, Erik H Hulzebos and Folkert J Meijboom

PLOS ONE, 2018, vol. 13, issue 10, 1-17

Abstract: Background: The various conditions causing a chronic increase of RV pressure greatly differ in the occurrence of RV failure, and in clinical outcome. To get a better understanding of the differences in outcome, RV remodeling, longitudinal function, and transverse function are compared between patients with pulmonary stenosis (PS), those with a systemic RV and those with pulmonary hypertension (PH). Materials and methods: This cross-sectional study prospectively enrolled subjects for cardiac magnetic resonance imaging (CMR), functional echocardiography and cardiopulmonary exercise testing. The study included: controls (n = 37), patients with PS (n = 15), systemic RV (n = 19) and PH (n = 20). Statistical analysis was performed using Analysis of Variance (ANOVA) with posthoc Bonferroni. Results: PS patients had smaller RV volumes with higher RV ejection fraction (61.1±9.6%; p

Date: 2018
References: View complete reference list from CitEc
Citations:

Downloads: (external link)
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0205196 (text/html)
https://journals.plos.org/plosone/article/file?id= ... 05196&type=printable (application/pdf)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0205196

DOI: 10.1371/journal.pone.0205196

Access Statistics for this article

More articles in PLOS ONE from Public Library of Science
Bibliographic data for series maintained by plosone ().