A comparison between measured and calculated central venous oxygen saturation in critically ill patients

Bruno De Oliveira, Malligere Prasanna, Malcolm Lemyze, Laurent Tronchon, Didier Thevenin and Jihad Mallat

PLOS ONE, 2018, vol. 13, issue 11, 1-13

Abstract: Background: Central venous oxygen saturation (ScvO2) is often used to help to guide resuscitation of critically ill patients. The standard gold technique for ScvO2 measurement is the co-oximetry (Co-oximetry_ScvO2), which is usually incorporated in most recent blood gas analyzers. However, in some hospitals, those machines are not available and only calculated ScvO2 (Calc_ScvO2) is provided. Therefore, we aimed to investigate the agreement between Co-oximetry_ScvO2 and Calc_ScvO2 in a general population of critically ill patients and septic shock patients. Methods: A total of 100 patients with a central venous catheter were included in the study. One hundred central venous blood samples were collected and analyzed using the same point-of-care blood gas analyzer, which provides both the calculated and measured ScvO2 values. Bland and Altman plot, intra-class correlation coefficient (ICC), and Cohen’s Kappa coefficient were used to assess the agreement between Co-oximetry_ScvO2 and Calc_ScvO2. Multiple linear regression analysis was performed to investigate the independent explanatory variables of the difference between Co-oximetry_ScvO2 and Calc_ScvO2. Results: In all population, Bland and Altman’s analysis showed poor agreement (+4.5 [-7.1, +16.1]%) between the two techniques. The ICC was 0.754 [(95% CI: 0.393–0.880), P

Date: 2018
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0206868

DOI: 10.1371/journal.pone.0206868

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