HPV self-testing for primary cervical cancer screening in Madagascar: VIA/VILI triage compliance in HPV-positive women

Anne-Caroline Benski, Manuela Viviano, Jéromine Jinoro, Milena Alec, Rosa Catarino, Joséa Herniainasolo, Pierre Vassilakos and Patrick Petignat

PLOS ONE, 2019, vol. 14, issue 8, 1-13

Abstract: Objective: To assess triage compliance and the effect of the time from screening to triage on follow-up among HPV-positive women. Methods: We recruited 1232 women in a screening campaign in Madagascar from February to October 2015. In the first period (February–May), HPV tests were performed remotely using the cobas test. In the second period (May–October), testing was performed on-site using the Xpert HPV assay. HPV-positive women were invited for triage with visual inspection with acetic acid (VIA) and Lugol’s iodine (VILI). Systematic biopsy and endocervical brushing were performed on all HPV-positive women for quality control. Three groups were defined according to time from HPV testing to triage invitation for HPV-positive women—Group I: delayed (> 3 months), Group II: prompt (24–48 hours), and Group III: immediate (

Date: 2019
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0220632

DOI: 10.1371/journal.pone.0220632

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