Evaluating antibiotic use and developing a tool to optimize prescribing in a family-centered HIV clinic in Eswatini

Tara E Ness, Ashish E Streatfield, Tandzile Simelane, Abiy Korsa, Sandile Dlamini, Danielle Guffey, Bhekumusa Lukhele and Alexander W Kay

PLOS ONE, 2021, vol. 16, issue 1, 1-10

Abstract: In a human immunodeficiency virus (HIV) clinic for children and their families in Eswatini, we sought to understand the use of antibiotics and identify specific areas for improvement. We performed a retrospective patient chart review as part of a quality improvement (QI) initiative to assess antimicrobial use before and after implementation of a standardized antimicrobial guide. For each prescribing period, 100 random patient encounters were selected for review if the indication for antibiotics, duration, and dose were consistent with World Health Organization (WHO) guidelines. Two physicians reviewed each encounter using a structured abstraction tool, with a third resolving discrepancies. Results were analyzed using a chi-square test of proportions and a structured survey was performed to assess perceptions of the guide. After the implementation of an antimicrobial guide, there was a significant decrease in the proportion of clinic visits with an antibiotic prescribed (p

Date: 2021
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0244247

DOI: 10.1371/journal.pone.0244247

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