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Delirium as a predictor of mortality and disability among hospitalized patients in Zambia

Justin K Banerdt, Kondwelani Mateyo, Li Wang, Christopher J Lindsell, Elisabeth D Riviello, Deanna Saylor, Douglas C Heimburger and E Wesley Ely

PLOS ONE, 2021, vol. 16, issue 2, 1-15

Abstract: Objective: To study the epidemiology and outcomes of delirium among hospitalized patients in Zambia. Methods: We conducted a prospective cohort study at the University Teaching Hospital in Lusaka, Zambia, from October 2017 to April 2018. The primary exposure was delirium duration over the initial 3 days of hospitalization, assessed daily using the Brief Confusion Assessment Method. The primary outcome was 6-month mortality. Secondary outcomes included 6-month disability, evaluated using the World Health Organization Disability Assessment Schedule 2.0. Findings: 711 adults were included (median age, 39 years; 461 men; 459 medical, 252 surgical; 323 with HIV). Delirium prevalence was 48.5% (95% CI, 44.8%-52.3%). 6-month mortality was higher for delirious participants (44.6% [39.3%-50.1%]) versus non-delirious participants (20.0% [15.4%-25.2%]; P

Date: 2021
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0246330

DOI: 10.1371/journal.pone.0246330

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