Prevalence and incidence of diabetic peripheral neuropathy in Latin America and the Caribbean: A systematic review and meta-analysis

Marlon Yovera-Aldana, Victor Velásquez-Rimachi, Andrely Huerta-Rosario, M D More-Yupanqui, Mariela Osores-Flores, Ricardo Espinoza, Fradis Gil-Olivares, César Quispe-Nolazco, Flor Quea-Vélez, Christian Morán-Mariños, Isabel Pinedo-Torres, Carlos Alva-Diaz and Kevin Pacheco-Barrios

PLOS ONE, 2021, vol. 16, issue 5, 1-29

Abstract: Aims: The objective of this systematic review and meta-analysis is to estimate the prevalence and incidence of diabetic peripheral neuropathy (DPN) in Latin America and the Caribbean (LAC). Materials and methods: We searched MEDLINE, SCOPUS, Web of Science, EMBASE and LILACS databases of published observational studies in LAC up to December 2020. Meta-analyses of proportions were performed using random-effects models using Stata Program 15.1. Heterogeneity was evaluated through sensitivity, subgroup, and meta-regression analyses. Evidence certainty was performed with the GRADE approach. Results: Twenty-nine studies from eight countries were included. The estimated prevalence of DPN was 46.5% (95%CI: 38.0–55.0) with a significant heterogeneity (I2 = 98.2%; p

Date: 2021
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0251642

DOI: 10.1371/journal.pone.0251642

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