The risk of psoriasis in patients with uveitis: A nationwide population-based cohort study

Yu-Yen Chen, Hsin-Hua Chen, Tzu-Chen Lo and Pesus Chou

PLOS ONE, 2021, vol. 16, issue 8, 1-10

Abstract: Objective: To evaluate whether the risk of subsequent psoriasis and psoriatic arthritis development is increased in patients with uveitis. Methods: In Taiwan’s national health insurance research database, we identified 195,125 patients with new-onset uveitis between 2001 and 2013. We randomly selected 390,250 individuals without uveitis who were matched 2:1 to uveitis cases based on age, sex and year of enrolment. The characteristics of the two groups were compared. Using multivariate Cox regression, hazard ratios (HRs) for psoriasis or psoriatic arthritis corresponding to uveitis were computed after adjustment for age, sex, insurance cost and comorbidities. In subgroup analyses, separate HRs for mild psoriasis, severe psoriasis and psoriatic arthritis were calculated. Results: The mean age of the study cohort was 50.2 ± 17.2 years. Hypertension, diabetes, hyperlipidaemia and obesity were more prevalent in the uveitis group (all p

Date: 2021
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0255492

DOI: 10.1371/journal.pone.0255492

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