Risk factors associated with the development of delirium in general ICU patients. A prospective observational study

Beatriz Lobo-Valbuena, Federico Gordo, Ana Abella, Sofía Garcia-Manzanedo, Maria-Mercedes Garcia-Arias, Inés Torrejón, David Varillas-Delgado and Rosario Molina

PLOS ONE, 2021, vol. 16, issue 9, 1-12

Abstract: Objective: We aimed to analyze risk factors related to the development of delirium, aiming for early intervention in patients with greater risk. Material and methods: Observational study, including prospectively collected patients treated in a single general ICU. These were classified into two groups, according to whether they developed delirium or not (screening performed using CAM-ICU tool). Demographics and clinical data were analyzed. Multivariate logistic regression analyses were performed to quantify existing associations. Results: 1462 patients were included. 93 developed delirium (incidence: 6.3%). These were older, scored higher on the Clinical Frailty Scale, on the risk scores on admission (SAPS-3 and SOFA), and had a greater number of organ failures (OF). We observed more incidence of delirium in patients who (a) presented more than two OF (20.4%; OR 4.9; CI95%: 2.9–8.2), and (b) were more than 74 years old albeit having

Date: 2021
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0255522

DOI: 10.1371/journal.pone.0255522

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