Incremental value of left atrial strain to predict atrial fibrillation recurrence after cryoballoon ablation

Andreea Motoc, Maria–Luiza Luchian, Esther Scheirlynck, Bram Roosens, Hadischat Chameleva, Maxim Gevers, Xavier Galloo, Berlinde von Kemp, Robbert Ramak, Juan Sieira, Carlo de Asmundis, Gian–Battista Chierchia, Julien Magne, Caroline Weytjens, Steven Droogmans and Bernard Cosyns

PLOS ONE, 2021, vol. 16, issue 11, 1-13

Abstract: Objective: Atrial fibrillation (AF) recurrence occurs in approximately 25% of the patients undergoing cryoballoon ablation (CBA), leading to repeated ablations and complications. Left atrial (LA) dilation has been proposed as a predictor of AF recurrence. However, LA strain is a surrogate marker of LA mechanical dysfunction, which might appear before the enlargement of the LA. The purpose of this study was to evaluate the additional predictive value of LA function assessed using strain echocardiography for AF recurrence after CBA. Methods: 172 consecutive patients (62.2 ± 12.2 years, 61% male) were prospectively analyzed. Echocardiography was performed before CBA. Blanking period was defined as the first three months post-ablation. The primary endpoint was AF recurrence after the blanking period. Results: 50 (29%) patients had AF recurrence. In the overall study population, peak atrial longitudinal strain (PALS) ≤ 17% had the highest incremental predictive value for AF recurrence (HR = 9.45, 95%CI: 3.17–28.13, p

Date: 2021
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0259999

DOI: 10.1371/journal.pone.0259999

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