Efficacy and safety of patients with chronic kidney disease undergoing left atrial appendage closure for atrial fibrillation

Chaofan Liu, Shaojie Han, Kaijun Cui and Fang Wang

PLOS ONE, 2023, vol. 18, issue 10, 1-15

Abstract: Background: The relative safety and efficacy of left atrial appendage closure (LAAC) for atrial fibrillation (AF) in patients with chronic kidney disease (CKD) have not been well defined. To evaluate the results in this cohort, we conducted a systematic review and meta-analysis of observational studies. Methods: We searched the PubMed, EMBASE, Web of Science, and Cochrane Library databases from inception to January 2023 for all relevant studies. Our inclusion criteria were met by twelve observational studies that included 61324 patients altogether. Results: Compared with no CKD group, in-hospital mortality (OR: 2.84, 95% CI: 2.12–3.81, p

Date: 2023
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0287928

DOI: 10.1371/journal.pone.0287928

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