Effect of autologous platelet-rich plasma on optical quality and visual outcomes following implantation of a trifocal diffractive intraocular lens

Kun-Hoo Na, Bo Young Lee, Hye Jin Cho and Joon Young Hyon

PLOS ONE, 2026, vol. 21, issue 1, 1-13

Abstract: Purpose: To evaluate the effect of autologous platelet-rich plasma (PRP) eye drops on optical quality and visual acuity in eyes implanted with a trifocal diffractive intraocular lens (IOL). Methods: In this retrospective cohort study of 128 eyes from 128 patients undergoing femtosecond laser-assisted cataract surgery with implantation of the CNWT Clareon PanOptix (Alcon Inc.) IOL, patients were assigned to one of two groups: the PRP group (n = 62), which received postoperative PRP eye drops, and the conventional treatment group (n = 66). At 3 weeks postoperatively, optical parameters—including the objective scatter index (OSI), modulation transfer function (MTF) cutoff, and Strehl ratio (SR)—were measured with a double-pass system. Uncorrected distance visual acuity (UDVA) and corrected distance visual acuity (CDVA) at 4 m, as well as uncorrected near visual acuity (UNVA) at 40 cm, were recorded in logMAR units. Results: The PRP group demonstrated superior optical quality across all measured parameters compared to the control group, with lower OSI (1.60 vs. 3.14), higher MTF cutoff (31.93 vs. 19.90 cycles/degree), and higher SR (0.15 vs. 0.12) (all P

Date: 2026
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0340880

DOI: 10.1371/journal.pone.0340880

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