Associated factors of health-related quality of life in Indonesian Women with Systemic Lupus Erythematosus: A cross-sectional within-cohort analysis

Euphemia Seto Anggraini Widyastuti, Josephine Lavina, Gabriel Justin Darmajaya and Stevent Sumantri

PLOS ONE, 2026, vol. 21, issue 4, 1-12

Abstract: Objective: This study aims to determine the effects of sleep quality along with age, marital status, socioeconomic status, depression, anxiety, disease activity, pain scale, and dose of corticosteroids on quality of life in women with SLE. Methods: Variables were assessed in 75 women with SLE using the Pittsburgh Sleep Quality Index (PSQI), Lupus Quality of Life (Lupus QoL), Depression, Anxiety, and Stress Scale-21 (DASS-21), and Mexican SLE Disease Activity Index (MEX-SLEDAI). Bivariate and multivariate analyses were performed to determine contributors to quality of life. Results: Of 75 subjects, 35 (46.7%) patients had poor sleep quality. The mean QoL score for patients is 84.27. Poor sleepers had impaired QoL in physical health (p = 0.003), emotional health (p = 0.007), pain (p = 0.003), and planning (p = 0.006), with fatigue (p

Date: 2026
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0341989

DOI: 10.1371/journal.pone.0341989

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