Airway management and anaesthetic interventions for children with cleft lip and/or palate undergoing general anaesthesia: Protocol for a systematic review and meta-analysis

Sharmin Akter Sumi, Kazi Mahzabin Arin, Shahriar Mohd Shams, Tanzila Rafique, Keertika Orchi, Arna Chowdhury, Mohammad Meshbahur Rahman and Md Atiqul Haque

PLOS ONE, 2026, vol. 21, issue 10, 1-9

Abstract: Background: Children with cleft lip and/or palate may present unique challenges during perioperative airway management because of altered upper-airway and craniofacial anatomy. These children frequently undergo surgical procedures requiring general anaesthesia and airway instrumentation. Several airway-management and anaesthetic techniques have been evaluated to facilitate tracheal intubation and reduce perioperative airway complications, but the comparative evidence from randomised controlled trials has not been systematically evaluated. Methods: This systematic review and meta-analysis will include randomised controlled trials involving children

Date: 2026
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0361327

DOI: 10.1371/journal.pone.0361327

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