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Biocompatibility evaluation of combined implantation material based on nitinol and mineralized bone matrix

Silant'eva T.A., Krasnov V.V., Nakoskin A.N. and Kubrak N.V.
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Silant'eva T.A.: Russian Ilizarov Scientific Center «Restorative Traumatology and Orthopaedics» of Ministry of Healthcare
Krasnov V.V.: Russian Ilizarov Scientific Center «Restorative Traumatology and Orthopaedics» of Ministry of Healthcare
Nakoskin A.N.: Russian Ilizarov Scientific Center «Restorative Traumatology and Orthopaedics» of Ministry of Healthcare

Russian Journal of Agricultural and Socio-Economic Sciences, 2016, vol. 55, issue 7, 8-17

Abstract: Purpose of the study consisted in testing biological compatibility of the implantation material structural and functional analogue of cancellous bone. The implant experimental sample included an elastic-and-fibrous component (constructed of titanium nickelide wire), a natively structured mineral component (fragments of xenogenic mineralized matrix), and a regulatory-and-trophic component (alloplasm combined with metabolically active substances ascorbic acid and glucose). The methods of orthoand heterotopic implantation, radiography, light and electron scanning miscroscopy, X-ray electron probe microanalysis demonstrated the improvement of biocompatibility, osteoinductivity and osteoconductivity of the implantation material components due to their synergic interaction.

Keywords: BONE DEFECT; IMPLANTATION; TITANIUM NICKELIDE; BONE MATRIX; BLOOD PLASM; ASCORBIC ACID; GLUCOSE (search for similar items in EconPapers)
Date: 2016
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