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Early life risk factors and their cumulative effects as predictors of overweight in Spanish children

Isabel Iguacel (), Laura Escartín, Juan M. Fernández-Alvira, Iris Iglesia, Idoia Labayen, Luis A. Moreno, María Pilar Samper and Gerardo Rodríguez
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Isabel Iguacel: University of Zaragoza
Laura Escartín: Instituto de Investigación Sanitaria Aragón (IIS Aragón)
Juan M. Fernández-Alvira: University of Zaragoza
Iris Iglesia: University of Zaragoza
Idoia Labayen: Universidad del País Vasco, UPV/EHU
Luis A. Moreno: University of Zaragoza
María Pilar Samper: Instituto de Investigación Sanitaria Aragón (IIS Aragón)
Gerardo Rodríguez: University of Zaragoza

International Journal of Public Health, 2018, vol. 63, issue 4, No 9, 512 pages

Abstract: Abstract Objectives To explore early life risk factors of overweight/obesity at age 6 years and their cumulative effects on overweight/obesity at ages 2, 4 and 6 years. Methods Altogether 1031 Spanish children were evaluated at birth and during a 6-year follow-up. Early life risk factors included: parental overweight/obesity, parental origin/ethnicity, maternal smoking during pregnancy, gestational weight gain, gestational age, birth weight, caesarean section, breastfeeding practices and rapid infant weight gain collected via hospital records. Cumulative effects were assessed by adding up those early risk factors that significantly increased the risk of overweight/obesity. We conducted binary logistic regression models. Results Rapid infant weight gain (OR 2.29, 99% CI 1.54–3.42), maternal overweight/obesity (OR 1.93, 99% CI 1.27–2.92), paternal overweight/obesity (OR 2.17, 99% CI 1.44–3.28), Latin American/Roma origin (OR 3.20, 99% CI 1.60–6.39) and smoking during pregnancy (OR 1.61, 99% CI 1.01–2.59) remained significant after adjusting for confounders. A higher number of early life risk factors accumulated was associated with overweight/obesity at age 6 years but not at age 2 and 4 years. Conclusions Rapid infant weight gain, parental overweight/obesity, maternal smoking and origin/ethnicity predict childhood overweight/obesity and present cumulative effects. Monitoring children with rapid weight gain and supporting a healthy parental weight are important for childhood obesity prevention.

Keywords: Overweight; Children; Early life risk factors; Prevention; Pregnancy (search for similar items in EconPapers)
Date: 2018
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DOI: 10.1007/s00038-018-1090-x

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