Sex Differences in Comorbidity and Frailty in Europe

Linda Juel Ahrenfeldt (), Sören Möller, Mikael Thinggaard, Kaare Christensen and Rune Lindahl-Jacobsen
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Linda Juel Ahrenfeldt: University of Southern Denmark
Sören Möller: OPEN – Odense Patient Data Explorative Network, Odense University Hospital
Mikael Thinggaard: University of Southern Denmark
Kaare Christensen: University of Southern Denmark
Rune Lindahl-Jacobsen: University of Southern Denmark

International Journal of Public Health, 2019, vol. 64, issue 7, No 7, 1025-1036

Abstract: Abstract Objectives To examine sex differences in prevalent comorbidity and frailty across age and European regions. Methods This is a cross-sectional study based on 113,299 Europeans aged 50+ participating in the Survey of Health, Ageing and Retirement in Europe from 2004–2005 to 2015. Sex differences in the Comorbidity Index and the Frailty Phenotype were investigated using ordinal logistic regressions. Results European women had generally higher odds of prevalent comorbidity (OR 1.11, 95% CI 1.07–1.15) and frailty (OR 1.56, 95% CI 1.51–1.62). Sex differences increased with advancing age. No overall sex difference in comorbidity was found in Western Europe, but women had more comorbidity than men in Eastern (OR 1.30, 95% CI 1.18–1.44), Southern (OR 1.23, 95% CI 1.15–1.30), and Northern (OR 1.08, 95% CI 1.01–1.16) Europe. Women were frailer than men in all regions, with the largest sex difference in Southern Europe (OR 1.84, 95% CI 1.72–1.96). Conclusions European women are frailer and have slightly more comorbidity than European men lending support for the male–female health survival paradox.

Keywords: Sex differences; Comorbidity; Frailty; Europe; SHARE (search for similar items in EconPapers)
Date: 2019
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DOI: 10.1007/s00038-019-01270-9

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