Psychometric Validation of the Growth Hormone Deficiency–Child Treatment Burden Measure (GHD-CTB) and the Growth Hormone Deficiency–Parent Treatment Burden Measure (GHD-PTB)

Meryl Brod (), Michael Højby Rasmussen, Suzanne Alolga, Jane F. Beck, Donald M. Bushnell, Kai Wai Lee and Aristides Maniatis
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Meryl Brod: The Brod Group
Michael Højby Rasmussen: Novo Nordisk A/S
Suzanne Alolga: The Brod Group
Jane F. Beck: The Brod Group
Donald M. Bushnell: Evidera | PPD
Kai Wai Lee: Novo Nordisk A/S
Aristides Maniatis: Rocky Mountain Pediatric Endocrinology

PharmacoEconomics - Open, 2023, vol. 7, issue 1, No 11, 138 pages

Abstract: Abstract Purpose The aim was to evaluate the measurement properties of the Growth Hormone Deficiency–Child Treatment Burden Measure–Child (GHD-CTB–Child), a patient-reported outcome (PRO) for children aged 9 to 0.70). Test–retest reliability was acceptable for the Physical, Emotional, and Overall domains of the GHD-CTB versions, and the Emotional and Overall domains of the GHD-PTB (intraclass correlation coefficient above 0.70). All but one of the convergent validity hypotheses for the GHD-CTB versions and all hypotheses for the GHD-PTB were proven (r > 0.40). Known-groups validity hypotheses were significant for length of time to administer the injections in the GHD-CTB versions (p

Date: 2023
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DOI: 10.1007/s41669-022-00373-z

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