A New Algorithm for Inferring Hybridization Events Based on the Detection of Horizontal Gene Transfers

Vladimir Makarenkov (), Alix Boc () and Pierre Legendre ()
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Vladimir Makarenkov: Université du Québec à Montréal
Alix Boc: Université de Montréal
Pierre Legendre: Université de Montréal

A chapter in Clusters, Orders, and Trees: Methods and Applications, 2014, pp 273-293 from Springer

Abstract: Abstract Hybridization and horizontal gene transfer are two major mechanisms of reticulate evolution. Both of them allow for a creation of new species by recombining genes or chromosomes of the existing organisms. An effective detection of hybridization events and estimation of their evolutionary significance have been recognized as main hurdles of the modern computational biology. In this article, we underline common features characterizing horizontal gene transfer and hybridization phenomena and describe a new algorithm for the inference and validation of the diploid hybridization events, when the newly created hybrid has the same number of chromosomes as the parent species. A simulation study was carried out to examine the ability of the proposed algorithm to infer correct hybrids and their parents in various practical situations.

Keywords: Additive tree; Phylogenetic tree; Horizontal gene transfer; Hybridization (search for similar items in EconPapers)
Date: 2014
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Persistent link: https://EconPapers.repec.org/RePEc:spr:spochp:978-1-4939-0742-7_17

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DOI: 10.1007/978-1-4939-0742-7_17

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